{"id":3453,"date":"2025-05-05T22:32:36","date_gmt":"2025-05-05T22:32:36","guid":{"rendered":"https:\/\/pacificpublichealth.ca\/?p=3453"},"modified":"2025-05-05T22:34:16","modified_gmt":"2025-05-05T22:34:16","slug":"antibiotics-childhood-asthma","status":"publish","type":"post","link":"https:\/\/pacificpublichealth.ca\/whats-new\/antibiotics-childhood-asthma\/","title":{"rendered":"The Link between Antibiotic Use in Infancy and Childhood Asthma \u2014 a Groundbreaking Study Supported by our Donors"},"content":{"rendered":"<p>Asthma is the <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/asthma#:~:text=Asthma%20is%20a%20major%20noncommunicable,common%20chronic%20disease%20among%20children\">number one chronic disease of childhood<\/a>, and the<a href=\"https:\/\/asthma.ca\/wp-content\/uploads\/2021\/11\/2021-Annual-Asthma-Survey-Report-3.pdf\"> third most common chronic disease in Canada<\/a>. 300 Canadians are diagnosed with asthma every day, and<a href=\"https:\/\/health-infobase.canada.ca\/datalab\/asthma-blog.html\"> it disproportionately affects younger children<\/a>. <strong>What if we could do something to prevent asthma from developing in the first place?<\/strong> That question is what prompted us to support research investigating whether asthma can be prevented, leading to reduced suffering, and ultimately, saving lives.<\/p>\n<p><span style=\"text-decoration: underline;\">The Asthma Burden<\/span><br \/>Preventing asthma in children is critically important for several reasons. Besides improved health and well-being, preventing asthma would greatly reduce costs to the healthcare system, like the cost of emergency room visits, costs for asthma medications, specialist appointments, and the like. <strong>Preventing asthma would help ease the financial burden on families as well.<\/strong> <a href=\"http:\/\/chrome-extension:\/\/efaidnbmnnnibpcajpcglclefindmkaj\/https:\/asthma.ca\/wp-content\/uploads\/2024\/11\/2024-National-Asthma-Survey-Findings-_-Asthma-Canada.pdf\" data-wplink-url-error=\"true\">A 2024 community asthma survey<\/a> conducted by Asthma Canada revealed that 66% of respondents experienced some level of financial strain related to managing their asthma.<\/p>\n<p>It would also decrease school absences and associated caregiver burden, while improving health equity, as asthma tends to disproportionately impact communities that experience inequities due to systemic barriers and <a href=\"https:\/\/pacificpublichealth.ca\/whats-new\/visualizing-the-social-determinants-of-health\/\">determinants of health<\/a>, often due to environmental factors like air pollution.<\/p>\n<p><span style=\"text-decoration: underline;\">New Research Leads to a Surprising Connection<\/span><br \/>When a child has an asthma attack, we don\u2019t often think about whether the child was given antibiotics or fed breast milk as an infant. Yet, researchers from the University of British Columbia (UBC) and the BC Centre for Disease Control (BCCDC) discovered there could be a link. The team examined whether <strong>reducing unnecessary antibiotic exposure during infancy and promoting breastfeeding can contribute to the global reversal of asthma and allergic disease. The short answer? Yes!<\/strong><\/p>\n<p>Prompted by evidence that in recent years, antibiotic use was decreasing drastically in babies, as was asthma in babies and children, <a href=\"http:\/\/www.bccdc.ca\/our-research\/people\/david-patrick\">Dr David Patrick, lead for antimicrobial resistance at BCCDC<\/a>, and his team of researchers, began investigating this connection by building two of the largest cohorts in BC and Manitoba to ever address the topic, studying administrative health data from 2001-2018.<\/p>\n<blockquote>\n<p>\u201cThe asthma folks did a double-take and said, \u2018Well, wait a minute. Asthma is coming down too, especially in kids.\u2019 And this raised the question for us as to whether these things [asthma and antibiotics] were connected.\u201d \u2014 Dr David Patrick<\/p>\n<\/blockquote>\n<p>Their research \u2014 published in <a href=\"https:\/\/www.frontiersin.org\/journals\/allergy\/articles\/10.3389\/falgy.2024.1491985\/full\"><em>Frontiers in Allergy<\/em><\/a> \u2014 found a significantly elevated risk of asthma and allergic diseases in children exposed to antibiotics in infancy in both provinces, after accounting for many other early life factors. <strong>Their research showed that antibiotics most likely caused the problem by disrupting development of a healthy microbiome<\/strong> \u2014 the healthy bacteria in the developing gut of the infant \u2014 which affects predisposition towards allergic responses, like asthma.<\/p>\n<p><span style=\"text-decoration: underline;\">Uncovering the Factors Behind the Rise of Childhood Asthma<\/span><br \/>According to Dr Patrick, there was a significant increase in childhood asthma in the 20th century, and two significant things were happening at once: doctors were dispensing antibiotics freely to babies and children, and corporations were advocating for the benefits of formula feeding. These two factors combined to create a problem.<br \/>It\u2019s important to note that breastfeeding is not linked to causing or preventing asthma; rather, it\u2019s that breastfeeding has a positive effect on children who are given antibiotics. Breast milk contains beneficial substances that help healthy bacteria in the body to recover when affected by antibiotics. Additionally, the recovery of healthy bacteria seems to have a positive impact on reducing the risk of allergies, including asthma, in children.<\/p>\n<p><span style=\"text-decoration: underline;\">Spreading the Word to Keep Children Healthy<\/span><br \/>Our Foundation has supported this project by teaming up with one of our valuable partners, <a href=\"https:\/\/www.tbvets.org\/\">TB Vets<\/a>, to help fund the knowledge translation of this work. Publishing these findings, creating an e-book for interested parties to download, and working with families, new parents, expecting parents, and primary care providers to create videos to educate about being antibiotic-wise, will help influence attitudes, policy, and potential investment in this work across Canada and beyond. <strong>This is applied public health work in real-time \u2014 translating evidence into change that advances equity and promotes health \u2014 and it is only with the support of our donors that this kind of work can take place.<\/strong><\/p>\n<blockquote>\n<p>\u201cIt\u2019s a lot of common sense things coming together to say that this inevitable asthma epidemic we saw emerging at the late twentieth century, may not be inevitable. We may be able to turn around large parts of it. And that\u2019s where the Foundation came in. They knew this story needed to be packaged so that people understand it. We\u2019re grateful to the Foundation for helping us get all this information together and out. For professionals, yes, but, because decisions are made by politicians and by the public, we need to reach that audience too.\u201d \u2014 Dr David Patrick<\/p>\n<p>\u201dFor 75 years, TB Vets Charitable Foundation has supported British Columbians suffering from respiratory emergencies. We are very proud to partner with our friends at PPHF to support research that has the potential to unlock the key to preventing asthma, one of the world\u2019s most pervasive respiratory illnesses.\u201d \u2014 Kandys Merola, President and CEO, TB Vets Charitable Foundation<\/p>\n<\/blockquote>\n<p><span style=\"text-decoration: underline;\">A Future with Reduced Asthma in Children<\/span><br \/>With these new findings, we hope that over time, there will be less unnecessary antibiotic use in infancy, the promotion of breastfeeding when possible, and consequently, fewer children suffering from asthma. <strong>This will improve the well-being of millions of children worldwide, and ease the financial burden of treatment-related costs on families, and the healthcare system.<\/strong><br \/>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<br \/>This project demonstrates the benefit of investing in prevention and public health. It is proactive rather than reactive, and by <a href=\"https:\/\/pacificpublichealth.ca\/resources\/upstream-101-decoding-public-health\/\">focusing upstream<\/a> on root causes, we collectively save time and resources, advance equity, and better protect community health and resiliency. <strong><a href=\"https:\/\/pacificpublichealth.ca\/donate\" target=\"_blank\" rel=\"noopener\">Please donate<\/a> to help support these kinds of important initiatives.<\/strong><\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>Asthma is the number one chronic disease of childhood, and the third most common chronic disease in Canada. 300 Canadians are diagnosed with asthma every day, and it disproportionately affects younger children. What if we could do something to prevent asthma from developing in the first place? That question is what prompted us to support [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":3464,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[19],"tags":[],"class_list":["post-3453","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-posts"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Link between Antibiotic Use in Infancy and Childhood Asthma \u2014 a Groundbreaking Study Supported by our Donors | Pacific Public Health Foundation<\/title>\n<meta name=\"description\" content=\"Asthma is the most common chronic disease in children \u2014 but what if we could prevent it? Groundbreaking research is uncovering links between infant antibiotic use, breastfeeding, and childhood asthma, and why prevention matters more than ever.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/pacificpublichealth.ca\/whats-new\/antibiotics-childhood-asthma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Link between Antibiotic Use in Infancy and Childhood Asthma \u2014 a Groundbreaking Study Supported by our Donors | Pacific Public Health Foundation\" \/>\n<meta property=\"og:description\" content=\"Asthma is the most common chronic disease in children \u2014 but what if we could prevent it? 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